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Figure 1 | BMC Blood Disorders

Figure 1

From: Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study

Figure 1

Schematics of the ZFA- target binding sites within the hemoglobin, beta gene. This figure graphically illustrates the binding sites of the 57 ZFAs that specifically target sequences within the genomic context of the hemoglobin, beta gene. Hits (blue, green, and gold bars) represent targets along the gene (red bars). ZFA hits in the graphic are color-coded based on spacer size (5 bp = Blue; 6 bp = Green; 7 bp = Gold).

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