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Table 4 Comparative Analysis of Body Composition and Plasma Leptin levels between the Sickle Cell Anaemia Patients and Control

From: Serum levels of leptin in Nigerian patients with sickle cell anaemia

^Subjects
    SCA Patients      Control    
Parameter Males
Boys
Men Total Females
Girls
Women Total Males
Boys
Men Total Females
Girls
Women Total
N (17) (8) (25) (16) (14) (30) (7) (3) (10) (7) (5) (12)
Age, yr 8.3 ± 1.4 25.7 ± 1.7 17.1 ± 1.6a 8.7 ± 0.8 23.3 ± 2.2 14.5 ± 2.1 9 ± 0.8 27.2 ± 0.2 10.8 ± 2.0 9.6 ± 1.2 22 ± 2.7 14.8 ± 2.2
Weight, kg 18.2 ± 0.9 35.9 ± 1.2a,b 23.9 ± 1.9 17.6 ± 1.6 41.3 ± 1.4 28.7 ± 2.4 18.2 ± 1.7 60.2 ± 1.5 20.8 ± 3.0 21.8 ± 0.8 49 ± 2.6 33 ± 4.4
BMI, kg/mm2 19 ± 0.4 18 ± 0.2a 18.7 ± 0.3a 18.7 ± 0.4a 19.3 ± 0.3a 19 ± 0.2 20.1 ± 0.4 23 ± 0.6 20.2 ± 0.4 21.8 ± 0.8 20.7 ± 0.7 21.2 ± 0.4
FM, kg 4.6 ± 0.8 8.4 ± 0.5a 5.8 ± 0.5 4 ± 0.3 8.7 ± 0.5 6.2 ± 0.5 4.6 ± 0.5c 19.3 ± 0.5c 5.5 ± 1.0c 6.5 ± 0.7 14.4 ± 0.8 21.3 ± 0.5
Leptin, ug/L 1.9 ± 0.9a,b 2.1 ± 0.07 2 ± 0.07b 3.7 ± 0.3a 2.1 ± 0.7a 4.1 ± 0.3a 2.5 ± 0.05c 2.4 ± 0.09c 2.5 ± 0.05c 10.1 ± 0.6 16.3 ± 1.4 12.7 ± 1.2
Leptin/FM 0.45 ± 0.03a,b 0.26 ± 0.02a,b 0.39 ± 0.04a,b 0.96 ± 0.09a 0.55 ± 0.06a 77 ± 0.06a 0.58 ± 0.05c 0.12 ± 0.004c 0.19 ± 0.06c 1.6 ± 0.1 1.1 ± 0.1 1.4 ± 0.1
  1. Data are mean ± SEM
  2. aP < 0.05 Significantly different in the same gender by age category [SCA Patients vs. Control (Mann-Whitney U test)]
  3. bP < 0.05 Significantly different in the between gender by age category in SCA Patients (Mann-Whitney U test)
  4. cP < 0.05 Significantly different in the between gender by age category in the Control Patients (Mann-Whitney U test)
  5. ^Age was set at ≤ 16 years for boy or girls and > 16 years for men or women