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Table 4 Comparative Analysis of Body Composition and Plasma Leptin levels between the Sickle Cell Anaemia Patients and Control

From: Serum levels of leptin in Nigerian patients with sickle cell anaemia

^Subjects

   

SCA Patients

    

Control

   

Parameter

Males

Boys

Men

Total

Females

Girls

Women

Total

Males

Boys

Men

Total

Females

Girls

Women

Total

N

(17)

(8)

(25)

(16)

(14)

(30)

(7)

(3)

(10)

(7)

(5)

(12)

Age, yr

8.3 ± 1.4

25.7 ± 1.7

17.1 ± 1.6a

8.7 ± 0.8

23.3 ± 2.2

14.5 ± 2.1

9 ± 0.8

27.2 ± 0.2

10.8 ± 2.0

9.6 ± 1.2

22 ± 2.7

14.8 ± 2.2

Weight, kg

18.2 ± 0.9

35.9 ± 1.2a,b

23.9 ± 1.9

17.6 ± 1.6

41.3 ± 1.4

28.7 ± 2.4

18.2 ± 1.7

60.2 ± 1.5

20.8 ± 3.0

21.8 ± 0.8

49 ± 2.6

33 ± 4.4

BMI, kg/mm2

19 ± 0.4

18 ± 0.2a

18.7 ± 0.3a

18.7 ± 0.4a

19.3 ± 0.3a

19 ± 0.2

20.1 ± 0.4

23 ± 0.6

20.2 ± 0.4

21.8 ± 0.8

20.7 ± 0.7

21.2 ± 0.4

FM, kg

4.6 ± 0.8

8.4 ± 0.5a

5.8 ± 0.5

4 ± 0.3

8.7 ± 0.5

6.2 ± 0.5

4.6 ± 0.5c

19.3 ± 0.5c

5.5 ± 1.0c

6.5 ± 0.7

14.4 ± 0.8

21.3 ± 0.5

Leptin, ug/L

1.9 ± 0.9a,b

2.1 ± 0.07

2 ± 0.07b

3.7 ± 0.3a

2.1 ± 0.7a

4.1 ± 0.3a

2.5 ± 0.05c

2.4 ± 0.09c

2.5 ± 0.05c

10.1 ± 0.6

16.3 ± 1.4

12.7 ± 1.2

Leptin/FM

0.45 ± 0.03a,b

0.26 ± 0.02a,b

0.39 ± 0.04a,b

0.96 ± 0.09a

0.55 ± 0.06a

77 ± 0.06a

0.58 ± 0.05c

0.12 ± 0.004c

0.19 ± 0.06c

1.6 ± 0.1

1.1 ± 0.1

1.4 ± 0.1

  1. Data are mean ± SEM
  2. aP < 0.05 Significantly different in the same gender by age category [SCA Patients vs. Control (Mann-Whitney U test)]
  3. bP < 0.05 Significantly different in the between gender by age category in SCA Patients (Mann-Whitney U test)
  4. cP < 0.05 Significantly different in the between gender by age category in the Control Patients (Mann-Whitney U test)
  5. ^Age was set at ≤ 16 years for boy or girls and > 16 years for men or women