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Table 3 Comparative Analysis of Body Composition and Plasma Leptin levels among the Sickle Cell Anaemia Patients in the Steady and Unsteady States

From: Serum levels of leptin in Nigerian patients with sickle cell anaemia

^SCA Patients
Parameter Steady
Males
Boys
Men Total Females
Girls
Women Total Unsteady
Males
Boys
Men Total Females
Girls
Women Total
(n) (6) (10) (16) (9) (6) (15) (7) (2) (9) (10) (5) (15)
Age, yr 8.3 ± 1.4b 25.7 ± 1.7a 17.1 ± 1.6a 8.7 ± 0.8 23.3 ± 2.2 14.5 ± 2.1 10 ± 1.2 17.5 ± 0.5 11.7 ± 1.5 10.9 ± 1.1 20.4 ± 2.2 15.1 ± 1.6
Weight, kg 17.8 ± 1.5b 40.5 ± 1.0a 31.9 ± 2.9a,b 19.3 ± 2.8a 43.3 ± 3.4a 26.1 ± 3.8a 18.8 ± 1.1 33.0 ± 0.2 22.0 ± 2.2 17.8 ± 1.4c 35.8 ± 1.3 28.8 ± 2.5
BMI, kg/m2 18.4 ± 0.2a 19.0 ± 0.3 18.7 ± 0.2 18.9 ± 0.5 19.6 ± 0.8a 19.2 ± 0.5 19.7 ± 0.1c 18.4 ± 0.4 19.4 ± 0.5 18.5 ± 0.5 17.9 ± 0.3 18.3 ± 0.4
FM, kg 3.6 ± 0.5a,,b 8.2 ± 0.4 6.5 ± 0.5 4.6 ± 0.6 9.6 ± 0.9a 6.0 ± 0.8 4.8 ± 0.5 8.9 ± 0.04 5.7 ± 0.7 4.4 ± 0.4 8.3 ± 0.9 5.7 ± 0.6
Leptin, ug/L 2.4 ± 0.03a,b 2.1 ± 0.05 2.2 ± 0.04a,b 4.2 ± 0.2a 6.9 ± 0.2a 5.3 ± 0.4a 1.6 ± 0.08 1.8 ± 0.3 1.6 ± 0.09 2.9 ± 0.1 3.0 ± 0.1 3.0 ± 0.09
Leptin/FM 0.7 ± 0.08b 0.27 ± 0.01b 0.43 ± 0.06b 1.04 ± 0.09a 0.72 ± 0.06a 0.98 ± 0.08a 0.52 ± 0.05 0.2 ± 0.03 0.42 ± 0.05 0.7 ± 0.05c 0.39 ± 0.06c 0.6 ± 0.05c
  1. n = Number of cases, Data are mean ± SEM
  2. aP < 0.05 Significantly different in the same gender by age category (Stable vs. Unstable (Mann-Whitney U test)
  3. bP < 0.05 Significantly different in the between gender by age category in steady HbSS Patients (Mann-Whitney U test)
  4. cP < 0.05 Significantly different in the between gender by age category in unsteady HbSS Patients (Mann-Whitney U test)
  5. ^Age was set at ≤ 16 years for boys or girls and > 16 years for men or women