Table 1 Demographic and Haematological Characteristics of the Sickle Cell Anaemia Patients

No. of cases

22

55

31

24

Sex, Male/Female

10/12

25/30

16/15

9/15

Age, yr

13.0 ± 1.5

15.3 ± 1.1

17.1 ± 1.6*

13.2 ± 1.1

^aHbF, %

1.3 ± 0.06

3.8 ± 0.2**

4.2 ± 0.2*

3.3 ± 0.2

Hb, g/dL

11.9 ± 0.2

8.3 ± 0.2**

8.9 ± 0.2*

7.4 ± 0.3

PCV, %

35.2 ± 0.5

25.5 ± 0.5**

27.3 ± 0.5*

23.2 ± 0.7

RC, %

1.7 ± 0.1

5.8 ± 0.3**

6.3 ± 0.4*

5.3 ± 0.6

% ICI

ND

6.7 ± 0.3

5.3 ± 0.3*

8.4 ± 0.4

MCHC, g/dL

34.0 ± 0.5

32.4 ± 0.2**

32.8 ± 0.3*

31.7 ± 0.2

MCH, pg

27.4 ± 0.5

23.9 ± 0.4**

25.0 ± 0.4*

22.6 ± 0.6

MCHC < 31 g/dL, n(%)

0(0)

10 (18.2)

3 (9.7)*

7 (29.2)

MCH < 25 pg, n(%)

3 (13.6)

35 (63.6)**

16 (51.6)*

19 (79.2)

ESR, mm/Hr

14.4 ± 3.5

35.1 ± 1.0**

25.7 ± 1.1*

38.4 ± 1.3

WBC, cells/uL × 10³

6.1 ± 0.2

11.7 ± 0.1**

11.4 ± 0.2*

12.1 ± 0.1

Neutrophils, cells/uL × 10³

3.4 ± 0.1

7.6 ± 0.1**

7.2 ± 0.2*

8.1 ± 0.2

Lymphocytes, cells/uL × 10³

2.0 ± 0.09

2.6 ± 0.1**

2.6 ± 0.1

2.4 ± 0.1

Monocytes, cells/uL × 10³

0.5 ± 0.04

1.0 ± 0.06**

0.9 ± 0.08

1.2 ± 0.09

Eosinophils, cells/uL × 10³

0.2 ± 0.02

0.4 ± 0.03**

0.5 ± 0.04*

0.3 ± 0.04

Basophils, cells/uL × 10³

0.08 ± 0.01

0.2 ± 0.02

0.1 ± 0.02

0.2 ± 0.04

Platelet count, cells/uL × 10³

241.8 ± 11.6

432.8 ± 82.6**

438.7 ± 11.1*

371.5 ± 16.2

RBC count, cells/uL × 10⁶

4.4 ± 0.07

3.5 ± 0.05**

3.6 ± 0.04*

3.3 ± 0.07