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Table 2 Comparisons of 103 adults with pagophagia and 15 adults with non-ice pica1

From: Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients

Characteristic

Report of pagophagia (n = 103)2

Pica without report of ice (n = 15)

Value of p3

Age, y

49 ± 15

52 ± 18

0.5056

Women, % (n)

90.3 (93)

100.0 (15)

0.2421

White, % (n)

74.8 (77)

80.0 (12)

0.4693

Body mass index, kg/m2

29.7 ± 7.6

30.1 ± 11.2

0.8857

Fatigue, % (n)

45.6 (47)

53.3 (8)

0.5764

Cardiopulmonary symptoms, % (n)

42.7 (44)

46.7 (7)

0.7730

Epithelial manifestations, % (n)

26.2 (27)

53.3 (8)

0.0361

Mental symptoms, % (n)

6.8 (7)

0 (0)

0.3758

Neuromuscular symptoms, % (n)

6.8 (7)

0 (0)

0.3758

Gastrointestinal blood loss, % (n)

36.9 (38)

33.3 (5)

0.7890

Reproductive blood loss, % (n)

43.7 (45)

20.0 (3)

0.0684

Epistaxis, % (n)

0 (0)

0 (0)

-

Hematuria, % (n)

1.0 (1)

0 (0)

0.8729

Medical blood loss, % (n)

5.8 (6)

20.0 (3)

0.0877

Chronic malabsorption, % (n)

8.7 (9)

40.0 (6)

0.0007

Unknown cause of iron deficiency/depletion, % (n)

8.7 (9)

6.7 (1)

0.7879

Hemoglobin, g/L

99 ± 21

110 ± 26

0.2471

MCV, fL

73.8 ± 13.1

82.7 ± 8.9

0.0026

RBC × 1012/L

4.16 ± 0.58

4.11 ± 0.95

0.8764

RDW, %

18.7 ± 3.9

17.7 ± 2.3

0.1637

Platelets × 109/L

336 ± 118

464 ± 247

0.0669

Lymphocytes × 109/L

1.8 ± 0.8

2.2 ± 0.7

0.1012

Neutrophils × 109/L

4.2 ± 2.1

4.8 ± 2.0

0.3587

SI, μmol/L

7 ± 5

7 ± 4

0.8412

TIBC, μmol/L

75 ± 13

77 ± 3

0.5761

TS, %

9 ± 8

9 ± 6

0.8805

SF, pmol/L

27 ± 22

27 ± 5

0.8883

Cancer in remission, %

8.7 (9)

0 (0)

0.2807

CVID, %

9.7 (10)

20.0 (3)

0.2154

Diabetes mellitus, %

13.6 (14)

0 (0)

0.1319

Hemochromatosis, %

1.0 (1)

0 (0)

0.8729

Anemia, % (n)

81.6 (84)

66.7 (10)

0.1808

Thrombocytosis, % (n)

16.5 (17)

46.7 (7)

0.0067

Thrombocytopenia, % (n)

2.9 (3)

6.7 (1)

0.4432

Iron deficiency, % (n)

68.0 (70)

66.7 (10)

0.9201

Iron deficiency with anemia, % (n)

55.3 (57)

40.0 (6)

0.2658

  1. 1Results are expressed as mean ± 1 SD or as percentage (n). Abbreviations: MCV, mean corpuscular volume; RBC, red blood cells; RDW, red blood cell distribution width; SI, serum iron; TIBC, total iron-binding capacity; TS, transferrin saturation; SF, serum ferritin; CVID, common variable immunodeficiency.
  2. 2Each of these patients reported pica for ice (pagophagia); some patients reported two or more pica items.
  3. 3Comparisons were made using Student's two-tailed t-test, Chi-square test, or Fisher's exact test, as appropriate.