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Table 2 Comparisons of 103 adults with pagophagia and 15 adults with non-ice pica1

From: Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients

Characteristic Report of pagophagia (n = 103)2 Pica without report of ice (n = 15) Value of p3
Age, y 49 ± 15 52 ± 18 0.5056
Women, % (n) 90.3 (93) 100.0 (15) 0.2421
White, % (n) 74.8 (77) 80.0 (12) 0.4693
Body mass index, kg/m2 29.7 ± 7.6 30.1 ± 11.2 0.8857
Fatigue, % (n) 45.6 (47) 53.3 (8) 0.5764
Cardiopulmonary symptoms, % (n) 42.7 (44) 46.7 (7) 0.7730
Epithelial manifestations, % (n) 26.2 (27) 53.3 (8) 0.0361
Mental symptoms, % (n) 6.8 (7) 0 (0) 0.3758
Neuromuscular symptoms, % (n) 6.8 (7) 0 (0) 0.3758
Gastrointestinal blood loss, % (n) 36.9 (38) 33.3 (5) 0.7890
Reproductive blood loss, % (n) 43.7 (45) 20.0 (3) 0.0684
Epistaxis, % (n) 0 (0) 0 (0) -
Hematuria, % (n) 1.0 (1) 0 (0) 0.8729
Medical blood loss, % (n) 5.8 (6) 20.0 (3) 0.0877
Chronic malabsorption, % (n) 8.7 (9) 40.0 (6) 0.0007
Unknown cause of iron deficiency/depletion, % (n) 8.7 (9) 6.7 (1) 0.7879
Hemoglobin, g/L 99 ± 21 110 ± 26 0.2471
MCV, fL 73.8 ± 13.1 82.7 ± 8.9 0.0026
RBC × 1012/L 4.16 ± 0.58 4.11 ± 0.95 0.8764
RDW, % 18.7 ± 3.9 17.7 ± 2.3 0.1637
Platelets × 109/L 336 ± 118 464 ± 247 0.0669
Lymphocytes × 109/L 1.8 ± 0.8 2.2 ± 0.7 0.1012
Neutrophils × 109/L 4.2 ± 2.1 4.8 ± 2.0 0.3587
SI, μmol/L 7 ± 5 7 ± 4 0.8412
TIBC, μmol/L 75 ± 13 77 ± 3 0.5761
TS, % 9 ± 8 9 ± 6 0.8805
SF, pmol/L 27 ± 22 27 ± 5 0.8883
Cancer in remission, % 8.7 (9) 0 (0) 0.2807
CVID, % 9.7 (10) 20.0 (3) 0.2154
Diabetes mellitus, % 13.6 (14) 0 (0) 0.1319
Hemochromatosis, % 1.0 (1) 0 (0) 0.8729
Anemia, % (n) 81.6 (84) 66.7 (10) 0.1808
Thrombocytosis, % (n) 16.5 (17) 46.7 (7) 0.0067
Thrombocytopenia, % (n) 2.9 (3) 6.7 (1) 0.4432
Iron deficiency, % (n) 68.0 (70) 66.7 (10) 0.9201
Iron deficiency with anemia, % (n) 55.3 (57) 40.0 (6) 0.2658
  1. 1Results are expressed as mean ± 1 SD or as percentage (n). Abbreviations: MCV, mean corpuscular volume; RBC, red blood cells; RDW, red blood cell distribution width; SI, serum iron; TIBC, total iron-binding capacity; TS, transferrin saturation; SF, serum ferritin; CVID, common variable immunodeficiency.
  2. 2Each of these patients reported pica for ice (pagophagia); some patients reported two or more pica items.
  3. 3Comparisons were made using Student's two-tailed t-test, Chi-square test, or Fisher's exact test, as appropriate.