Table 2 Therapies for various angioedemas [6, 22, 26, 27, 29, 33, 34].
From: Hereditary angioedema: New therapeutic options for a potentially deadly disorder
Angioedema type | Therapies* | |
|---|---|---|
HAE type 1 HAE type 2 Inherited angioedema with normal C1 inhibitor | Acute treatment C1 inhibitor Kallikrein inhibitor Bradykinin β2-receptor inhibitor | Prophylaxis C1 inhibitor Danazol Antifibrinolytics are used in clinical practice. There are no approved therapies for medical/dental procedure prophylaxis. |
Acquired | Acute treatment C1 inhibitor is the treatment of choice for laryngeal attacks. Doses greater than 1000 units may be required. | Prophylaxis Treatment of underlying disease. Antifibrinolytics are the first choice for long-term therapy, followed by attenuated androdgens. |
Angiotensin converting enzyme inhibitor induced | ACE inhibitor discontinuation. | |
Idiopathic | Antihistamines followed by glucocorticoids. | |