Table 5 Quality of life scores of child self-report classified by clinical characteristics of the patients
From: Factors affecting health-related quality of life in Thai children with thalassemia
| Â | Â | Child self-report | |||||
|---|---|---|---|---|---|---|---|
| Â | Â | Total summary score | Physical health | Psychosocial health | Emotional functioning | Social functioning | School functioning |
| Â | Â | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
Diagnosis (n = 310) | |||||||
   β-thalassemia | n = 165 | 76.23(11.99) | 77.46(13.20) | 74.74(13.20) | 76.03(17.36) | 83.60(15.57) | 67.06(14.92) |
   Homozygous β-thalassemia | n = 15 | 71.81(10.83) | 73.54(13.91) | 71.89(12.89) | 70.00(16.58) | 80.00(13.70) | 62.67(15.68) |
   Hb H | n = 130 | 77.54(10.72) | 79.49(14.68) | 76.63(12.28) | 76.23(15.76) | 84.04(13.67) | 69.23(17.19) |
P-value | 0.145 | 0.187 | 0.234 | 0.368 | 0.424 | 0.103 | |
Age at onset of anemia <2 and age at first transfusion <4 years old (n = 241) | |||||||
   Yes | n = 75 | 72.75(11.33) | 73.96(15.95) | 73.51(12.64) | 74.53(14.71) | 78.53(17.10) | 63.26(14.94) |
   No | n = 166 | 77.72(11.08) | 79.01(14.67) | 76.02(12.73) | 76.08(15.99) | 85.49(13.45) | 69.52(16.15) |
P-value | 0.002 | 0.023 | 0.099 | 0.228 | 0.003 | 0.003 | |
Complications (n = 314) | Â | Â | Â | Â | Â | Â | |
   Yes | n = 19 | 77.52(14.37) | 77.14(19.05) | 77.81(16.21) | 76.32(19.57) | 84.21(16.52) | 72.63(15.13) |
   No | n = 295 | 76.60(11.22) | 78.30(14.50) | 75.34(12.52) | 75.83(16.46) | 83.66(14.66) | 67.56(15.97) |
P-value | 0.773 | 0.941 | 0.169 | 0.628 | 0.661 | 0.228 | |
Having a severe condition* (n = 314) | Â | Â | Â | Â | Â | ||
   Yes | n = 113 | 74.07(12.05) | 75.97(15.93) | 74.12(12.77) | 75.53(15.27) | 78.89(16.86) | 63.73(16.98) |
   No | n = 201 | 78.10(10.79) | 79.49(15.93) | 76.26(12.71) | 76.04(17.37) | 86.39(12.68) | 69.63(15.09) |
P-value | 0.004 | 0.077 | 0.097 | 0.417 | <0.001 | 0.021 | |
Serum ferritin level (n = 127) | Â | Â | Â | Â | Â | ||
   <2500 ng/mL | n = 79 | 76.50(12.83) | 78.20(15.66) | 75.25(13.38) | 74.18(18.70) | 84.24(15.19) | 66.27(14.82) |
   >2500 ng/mL | n = 48 | 76.61(10.14) | 76.88(13.03) | 75.76(12.73) | 80.42(14.39) | 84.06(13.94) | 64.89(15.38) |
P-value | 0.0897 | 0.426 | 0.903 | 0.100 | 0.726 | 0.741 | |
Pre-transfusion Hb level 3 months prior to QOL assessment (n = 265) | Â | Â | Â | ||||
   <7 g/dL | n = 49 | 73.51(13.06) | 75.06(17.84) | 73.82(13.41) | 74.03(14.21) | 76.84(16.64) | 64.90(18.78) |
   7-9 g/dL | n = 159 | 75.59(11.09) | 77.10(14.61) | 73.78(13.21) | 87.01(13.09) | 84.03(14.08) | 66.00(15.55) |
   >9 g/Dl | n = 57 | 79.82(10.21) | 81.03(13.35) | 79.18(17.44) | 76.49(17.44) | 87.01(13.09) | 74.03(14.21) |
   P-value | 0.012 | 0.163 | 0.016 | 0.474 | 0.002 | 0.008 | |